Management: Use a lower initial propranolol dose and be more cautious during propranolol dose titration when combined with strong CYP1A2 inhibitors
The carbimazole dose was increased to 40 mg po bid and she was started on cholestyramine 4 g po bid, and we increased the propranolol to 40 mg po tid and decreased the
2
, dosing, pharmacodynamics, pharmacokinetics, monitoring, relevant interactions) of propylthiouracil pertinent for healthcare team members in the
2 Propranolol caused a highly significant increase in serum reverse T3 concentrations with lesser changes in other serum thyroid hormone levels, whereas metoprolol did not have this effect
Methimazole, a thionamide medication, is crucial in treating hyperthyroidism and related conditions
(If hydrocortisone unavailable: 125 mg IV methylprednisolone
at a dose of 2 mg/kg/day, and stopped when the patient becomes euthyroid
5-2 times the upper limit of normal) can be treated starting with 10 to 20 mg of methimazole, and severe hyperthyroidism (free
, propranolol, 10 to 20 mg every eight hours), titrated to a dosage that provides symptomatic relief, is recommended for patients who are symptomatic during the Summary
If it continues for a long time, the heart and arteries may not function properly
Sympathetic effects mediated by β-receptors, such as the cardiac and peripheral vasodilator effects, seem to be especially prominent in hyperthyroidism