1 –4 To fill this gap, over the last 25 years, patients have developed a
According to the CDC, from 2010 to 2014, two of the top 10 drugs responsible for overdose deaths were benzodiazepines
If benzodiazepines are taken for two weeks or longer, it is recommended that the user should not abruptly stop taking this drug
Risk with antidepressants alone
The only medication with a long half-life is clonazepam (Klonopin)
It is used to treat major depressive disorder, generalized anxiety disorder, and other related conditions
Benzodiazepines may actually interfere with the extinction of fear conditioning and/or potentiate the acquisition of fear response and worsen recovery from trauma
High-dose use relative to tolerance can incur risks of overwhelming sedation, confusion, and even respiratory depression
¥ Agomelatine may be hepatotoxic and is contraindicated with any degree of liver impairment
93 The clinical recommendations and practice points presented in this guide are based on the best available evidence
benzodiazepines, cannabis (or cannabis derivatives)‡ (Pristiq) and duloxetine (Cymbalta) (1)
What is the difference between dependence and withdrawal reactions? A comparison of benzodiazepines and selective serotonin re-uptake inhibitors: SSRi and dependence