Prevention and treatment of chemotherapy- and radiotherapy-induced nausea and vomiting— (follow-on dose based on body surface area) By mouth
See more Studies have shown that Zofran can help children keep oral fluids down rather than vomiting them up
Evidence-based guidelines agree that antidiarrheal medications should not be used, but some guidelines recommend the antiemetic ondansetron (Zofran) as an
Pediatric Appropriate studies have not been performed on the relationship of age to the effects of ondansetron in children younger than 4 years of age
In children with gastroenteritis and dehydration, a single dose of oral ondansetron reduces vomiting and facilitates oral rehydration and may thus be well
1 Symptoms of AGE are pathogen-dependent and
TORONTO, April 20 - A single oral dose of the antiemetic Zofran (ondansetron) can reduce vomiting by more than half and facilitate oral rehydration in children with
May be given to children aged 4 and older
PONV in adults: 16 mg single dose given one hour before anesthesia
001) and were half as likely to be treated with intravenous rehydration (14% vs
1 interaction
muscle pain or cramps
n remains a challenge for the pediatrician because several antiemetics are prescribed as “off-label,” outside their authorized drug label
Common uses of ondansetron include the prevention of chemotherapy-induced and radiation-induced
TABLE 1 Clinical trials: Use of oral ondansetron for gastroenteritis-related vomiting in infants and children: Study, year: Patients, n: Age range: Inclusion criteria: Dosing (patient weight or age) Results after ondansetron treatment, RR (95% CI) Persistent emesis in ED: Receiving IV or NG fluids: Hospital admission: Ramsook et al , 2002
Maximum: 8 mg/dose
Take this medication exactly as directed It has not been confirmed that ondansetron is safe and effective for use in children younger than 4 years
This page from Great Ormond Street Hospital (GOSH) explains what ondansetron is, how it is given and some of the possible side effects
Narrative: Three studies examined administration of weight-based oral ondansetron (Zofran) vs
Zanamivir (trade name Relenza®) is approved for treatment of flu in children 7 years and older
ZOFRAN is indicated for the prevention of nausea and vomiting associated with: highly emetogenic cancer chemotherapy, including cisplatin greater than or equal to 50 mg/m 2
Ondansetron is approved to help prevent nausea and vomiting in certain children