Fluconazole may significantly increase the blood levels of atorvastatin
Warfarin (Coumadin, Jantoven) is a blood thinning medication
The triazole antifungals fluconazole and voriconazole inhibit CYP2C9 and can increase the risk of serious bleeding in patients taking warfarin
Fluconazole is predicted to increase the
decrease the risk of cardiovascular disease and the risk of death from it
Applies to: fluconazole and Lipitor (atorvastatin) Fluconazole may significantly increase the blood levels of atorvastatin
Applies to: Diflucan (fluconazole) and atorvastatin
fluconazole is coadministered with HMG-CoA reductase inhibitors metabolized through CYP3A4, such as atorvastatin and simvastatin, or through CYP2C9, such as fluvastatin
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6 Pharmacy updates advise caution when co-administering fluconazole with atorvastatin, with Objective: To report a case of rhabdomyolysis after concomitant use of simvastatin, a commonly used hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, and fluconazole, an azole antifungal agent
It is created by eHealthMe based on reports from the FDA, and is updated regularly
3 4 Although fluconazole is considered only as a mild to moderate inhibitor of CYP3A4, 4 there have been reports of rhabdomyolysis when
Diflucan has active ingredients of fluconazole
Currently, eHealthMe is studying from 71,051 Atorvastatin The in vitro antimycotic effect of atorvastatin, fluconazole and nystatin was determined using the broth microdilution method according to the M27-A3 guideline of the Clinical and laboratory standards institute (CLSI)
Fluconazole may increase the blood levels of amLODIPine
All statins except pravastatin and rosuvastatin are considered lipophilic
17 We identified a total of 112 reported cases of statin-induced rhabdomyolysis published
If concomitant therapy
If concurrent treatment is necessary, monitor for symptoms of myopathy and rhabdomyolysis, and monitor creatine kinase
The structural formula is: Fluconazole, USP is a white or almost white crystalline powder which is freely soluble in methanol; soluble in The metabolism of statins is described by basic phar-macokinetic principles
Some statins are more likely to interact with colchicine than others
Fluconazole is also used to treat meningitis (infection of the membranes covering the brain and spine) caused Fluconazole is a white crystalline solid which is slightly soluble in water and saline
Dosage adjustments are recommended for patients with moderate to severe renal impairment (CrCl <= 50 mL/min) receiving multiple doses of the drug
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